The study reveals that α-pinene has a sleep-enhancing effect, increasing sleep quantity but not changing sleep quality. This effect is fully blocked by flumazenil, an antagonist of the GABA A-BZD receptor. Phytoncides from pine trees, including α-pinene and 3-carene, also have sleep-enhancing effects as a positive modulator of GABA. Similar to α-pinene, 3-carene shows a sleep-enhancing effect by acting as a positive modulator for the GABAA-BZD receptor.
Two hydrogenated monoterpenes (α-pinene and 3-carene) from Cupressus sempervirens were tested against Sitophilus zeamais in the laboratory to evaluate their contact and fumigation effects on adult mortality. Combined applications of Detech®+α-pinene demonstrated the highest mortality on R. dominica (40. 4 mortality), S. zeamais (27. 9), and S. granarius (18. 5), while no.
The study also highlights the potential of α- and β-pinene, including their cytogenetic, gastroprotective, anxiolytic, and neuroprotective properties. Pinene increases sleep quality and protects brain cells against oxidative damage. It can have sedative or anxiolytic effects in zebrafish and may have different medicinal properties.
Insecticides like α-pinene inhibit early root growth and cause oxidative damage in root tissue through enhanced generation of ROS. From the 38th day on, the insecticide effect decreased, causing about 30 mortality in the target insect at 71 days. The residual effect of phytoncides from pine trees is also reported to decrease after the 38th day, indicating that the insecticide effect decreases over time.
Article | Description | Site |
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Therapeutic Potential of α- and β-Pinene: A Miracle Gift … | by B Salehi · 2019 · Cited by 498 — α-pinene and zolpidem were supplemented orally pre-pentobarbital injection (45 mg/kg), α-pinene displayed sleep improving activity through a direct binding … | pmc.ncbi.nlm.nih.gov |
Evaluation of the Insecticidal Activities of α-Pinene and 3- … | by JD Langsi · 2020 · Cited by 72 — The high activity of α–pinene and 3-carene has been suggested to be due to their ability to penetrate the insects‘ respiratory system (26,27). In this study, 3 … | mdpi.com |
α-Pinene odor exposure enhances heat stress tolerance … | by N Ensaka · 2020 · Cited by 4 — This study showed that pinene odor stimulation exerts bioactivity and modulates gene expression. Odor stimulation with S-(−)- and R-(+)-α–pinene increased heat … | sciencedirect.com |
📹 🍋Top 10 Terpenes and What They Do
These are the TOP 10 TERPENES in CANNABIS, and what each of them can do… UNLOCK EXCLUSIVE CHANNEL PERKS!
Does Pine Make You Sleepy?
Our studies indicate that phytoncides from pine trees, such as α-pinene and 3-carene, act as positive modulators of GABAA-BZD receptors, potentially enhancing sleep. Pineapple is rich in sleep-supportive nutrients, including melatonin, vitamin C, magnesium, and fiber, which help regulate the sleep-wake cycle and promote relaxation. Melatonin, which can be increased by consuming foods like pineapple, assists in resetting the circadian rhythm rather than inducing immediate sleepiness.
Sleep expert Dave Gibson supports the efficacy of the trending "pineapple hack" on TikTok, noting that Montmorency tart cherries may provide even more significant sleep benefits. TikToker Emma Leigh claims that pineapple can elevate melatonin levels in the body by 240%, enhancing sleep quality. Registered dietitian Keri Glassman lists pineapple among her top five foods for better sleep due to its melatonin content. Additionally, tryptophan in pineapple can boost melatonin and serotonin levels, contributing to a relaxed state conducive to sleep.
The effects of eating pineapple before bed can vary, and while some advocate its sleep-inducing properties, others caution that it may cause mouth irritation. Popular items such as Swiss stone pine beds are reported to enhance sleep quality. Research also shows that pine essential oil and pine needle tea may improve overall well-being and have anti-fatigue properties, further linking pine-related products to better sleep quality.
What Is Alpha Pinene Good For?
Alpha-pinene, a prominent terpene found in cannabis and various other plants, exhibits positive effects on scopolamine-induced memory and learning impairments, making it a potential candidate in dementia management. Studies suggest that alpha-pinene enhances concentration and focus, while beta-pinene generally has mood-lifting effects. This compound, prevalent in pine trees, rosemary, and household products like Pine-Sol, is recognized for its aromatic qualities reminiscent of a pine forest.
Beyond its appealing scent, alpha-pinene possesses notable health benefits. It has demonstrated anti-inflammatory and neuroprotective properties, effectively improving cytokine levels in nervous system-related diseases. Research highlights its capability to stimulate apoptosis in cancer cells, showing promise in treating various types of cancers such as ovarian and liver cancers. Additionally, alpha-pinene has been traditionally used to alleviate respiratory infections.
There are two primary variants of pinene: alpha-pinene, the more common form associated with cannabis, and beta-pinene, which is less prevalent. Both forms have shown potential synergistic effects in inhibiting tumor growth and managing inflammatory diseases. Overall, alpha-pinene's multifaceted properties—ranging from energizing effects to its role in mental health and cancer treatment—underscore its significance and appeal in therapeutic applications and as an ingredient in CBD products. As research continues, the potential of alpha-pinene may further illuminate its benefits in health and wellness.
Which Terpene Makes You Giggle?
Limonene stands out as the top terpene for inspiring laughter due to its mood-enhancing qualities, akin to a burst of sunshine that can lift spirits and evoke amusement. While terpenes don't chemically trigger laughter, many users report feeling giggly after exposure, suggesting a correlation rather than direct causation. Finding the right environment or companion can also play a crucial role in enhancing the giggly experience. Terpenes with cerebral effects directly influence mood, happiness, and laughter.
Among cannabis strains, sativa-dominant varieties are particularly known for promoting laughter and joy. Limonene is a prevalent monoterpene in cannabis and is particularly effective at inducing humor. Other mood-boosting terpenes worth noting include myrcene, which promotes relaxation and can spur a carefree giggle session, and pinene, which can provide energy and uplift. Specific strains, such as Liberty Haze, exhibit strong terpene profiles that foster a happy and social atmosphere.
For optimal laughter, it is recommended to choose strains high in THC and those with uplifting terpenes such as myrcene, limonene, and pinene. Sativa or balanced hybrid strains are generally linked to energizing effects that may lead to giggling. Individual experiences can vary, so exploring different combinations of terpenes, cannabinoids, and strains can help users discover their ideal recipe for laughter. Ultimately, the right cannabis selection can greatly enhance one's mood and cultivate a blissful state.
What Is The Strongest Herb For Insomnia?
Studies suggest that valerian, a flowering grassland plant, may help reduce the time it takes to fall asleep and improve overall sleep quality. Among various valerian species, the roots of Valeriana officinalis have been the focus of significant research. Valerian root is commonly taken in doses of 300–600 mg and is recognized for its potential to alleviate sleep disorders. Other herbs that may aid sleep include hops, passion flower, black cohosh, ashwagandha, hibiscus, and elderberry.
Additionally, chamomile, lemon balm, theanine, St. John's Wort, and rhodiola have also been linked to improvements in insomnia and anxiety. Lavender is another popular herb known to promote restful sleep. Overall, valerian and these herbs serve as natural sleep aids, providing alternatives for those seeking better sleep solutions.
Is Pinene A Good Terpene?
Pinene, a prevalent terpene in the cannabis industry, has the unique ability to both enhance and reduce cannabinoid function. It is found not only in cannabis but also abundantly in various plants such as cedar, basil, and eucalyptus. Pinene is recognized for its potential therapeutic properties, including anxiety reduction, improved lung function, and possible support in cancer treatments. Its refreshing pine scent enhances the appeal of cannabis strains that contain it.
Pinene exists in two forms: alpha-pinene and beta-pinene. Alpha-pinene tends to provide energizing effects, improving focus and concentration, while beta-pinene may offer more relaxing qualities, elevating mood and serotonin levels. In terms of physical benefits, pinene is noted for its anti-inflammatory properties, making it valuable in pain management and reducing swelling associated with various conditions.
The terpene’s medicinal potential is significant, with studies suggesting its effectiveness as a bronchodilator, anxiety reliever, and even in combating short-term memory impairment. This makes pinene-rich strains popular among consumers seeking relief and therapeutic benefits. Overall, pinene stands out as a versatile and beneficial terpene in both cannabis and nature, contributing to improved mental and physical well-being while delivering the familiar essence of a fresh pine forest. Its multifaceted effects make it a key component in various strains aimed at enhancing overall therapeutic experiences.
How Is The AHI Used For Sleep Apnea?
Alpha-pinene and beta-pinene, while similar, exhibit distinct chemical properties that influence their functionalities. Alpha-pinene is characterized by the scent commonly associated with pine trees, whereas beta-pinene has a more herbal and earthy aroma. The Apnea-Hypopnea Index (AHI) is a crucial diagnostic metric for sleep apnea, quantifying the average occurrences of apneas (complete cessation of breathing) and hypopneas (partial reduction in airflow) per hour during sleep.
To calculate the AHI, doctors divide the overall number of these events by the total hours slept, with each event requiring a duration of at least 10 seconds to be included. A higher AHI denotes more frequent breathing disruptions, indicating a potential diagnosis of sleep apnea.
Obstructive sleep apnea (OSA) leads to airway collapse during sleep, resulting in significant respiration reduction or cessation. The AHI score, which reflects the frequency of breathing interruptions, is instrumental in diagnosing and assessing the severity of OSA. Treatment often involves lifestyle modifications, such as weight loss and smoking cessation. Understanding the AHI is pivotal in the evaluation and management of sleep apnea, as it offers insights into the frequency of apneic events per hour.
The AHI serves as a vital tool for clinicians, providing a clear metric to classify the severity of a patient's sleep apnea. Conducting a sleep study yields an AHI score, essential for determining the disorder's impact. In essence, the apnea-hypopnea index quantifies the nature and frequency of breathing disruptions during sleep, guiding both diagnosis and potential treatment pathways for individuals with sleep apnea.
Is Pinene Good For Anxiety?
A 2012 study demonstrated that both alpha and beta pinene inhibited the growth of MRSA, a leading cause of drug-resistant staph infections, and reduced infection risk in lung tissue. Those using cannabis to alleviate anxiety may find pinene beneficial; however, terpenes like Guaiol and Terpinolene are generally not recommended for anxiety relief, as they may exacerbate symptoms in some individuals. Pinene is an oily, clear liquid derived from various plants, including cannabis, pine trees, orange peels, dill, basil, and parsley, with around 200, 000 identified occurrences in the plant kingdom.
Research indicates that inhaled pinene can help mitigate anxiety symptoms, particularly in animal models. Its potential neuroprotective properties and cognitive benefits are noted, especially in reducing inflammation and promoting relaxation. Alpha-pinene, in particular, is associated with increased focus and reduced anxiety, while beta-pinene is linked to neuroprotective effects. Animal studies consistently show positive outcomes for both isomers regarding anxiety and depression-like behaviors.
Pinene-rich cannabis strains are favored in medical marijuana circles for their stress and anxiety-reducing properties, supported by a growing body of research. While the study of pinene's effects on anxiety is still evolving, initial findings are promising and point toward its potential for promoting healthful relaxation, restful sleep, and cognitive enhancement. Meanwhile, Caryophyllene is highlighted as a top choice for anxiety relief among terpenes. Overall, pinene emerges as a valuable component in the landscape of terpenes beneficial for mental health.
What Are The Effects Of Alpha Pinene?
Alpha-Pinene is a prominent terpenoid found in essential oils, known for its energizing effects and potential health benefits. However, it may pose risks such as skin allergies and kidney damage. Regulatory agencies like OSHA and NIOSH set permissible airborne exposure limits at 100 ppm (as Turpentine) over an 8 or 10-hour work shift. This compound is recognized for enhancing concentration, focus, and aiding short-term memory retention, making it potentially beneficial for counteracting THC-induced memory loss.
Alpha-pinene showcases various pharmacological effects including anti-inflammatory properties, bronchodilation, and antimicrobial activity. Animal studies indicate its neuroprotective abilities, potentially aiding conditions like Alzheimer’s. The compound increases skin penetration of drugs and inhibits inflammatory pathways via PGE1 and NF-κB. Additionally, α-pinene has been shown to lead to apoptosis in certain contexts, reduce seizures, and alleviate pain responses in experimental settings.
While beneficial, excessive exposure may result in dizziness, confusion, or seizures. Both α- and β-pinene are investigated for effects on cytogenetics, gastroprotection, and neuroprotection among others. Sourced from conifers, α-pinene is valued as a polyphenolic compound, exhibiting anti-inflammatory, antioxidant, and apoptotic properties. Overall, its diverse bioactivity warrants further research, particularly in neurodegenerative diseases where oxidative stress is a concern. It’s important to balance the potential therapeutic effects with known risks, as well as to explore its applications in traditional and alternative medicinal practices.
Does Pine Contain Testosterone?
Testosterone has been identified in the pollen of Scots pine (Pinus sylvestris), with an estimated concentration of 0. 8 micrograms per 10 grams of pollen. This discovery has led to pine pollen being popularized as a supplement for boosting testosterone levels. A study cited in the journal Phytotherapy Research indicated that an eight-week regimen of pine pollen extract significantly elevated testosterone levels in men suffering from low testosterone. Beyond testosterone enhancement, pine pollen is believed to have anti-aging effects and combat fatigue.
Research highlights that pine pollen contains four primary male sex hormones: testosterone, dehydroepiandrosterone (DHEA), androstenedione, and androsterone. These hormones are thought to contribute to testosterone regulation and balance estrogen with androgens in the body. Despite the small amounts of testosterone present, its potential impact on human androgen levels should not be underestimated.
Investigations suggest that while pine pollen contains phytoandrogens—plant-derived compounds that mimic human hormones like testosterone—the effectiveness of these supplements can vary among individuals. Additionally, it does not inhibit the body's natural testosterone production and has historically been utilized in traditional Chinese medicine for addressing low testosterone issues.
Exploration into combining pine pollen with adaptogenic herbs presents an avenue for enhancing testosterone levels and overall vitality. Structured cycles for administering these herbal combinations could benefit holistic wellness. In summary, the role of pine pollen as a natural source of testosterone and its potential health benefits makes it a point of interest in both scientific research and traditional health practices.
Is Alpha-Pinene Good For Your Skin?
A study in the American Journal of Chinese Medicine (2015) highlighted the anti-inflammatory benefits of alpha-pinene, particularly in animal models. Following this, research in 2018 demonstrated that alpha-pinene can protect skin from UV radiation due to its anti-inflammatory and antioxidant properties. Additionally, studies have indicated that pinenes enhance drug penetration through the skin (Almirall et al.
1996) and exert anti-inflammatory effects by inhibiting specific signaling pathways like MAPK and nuclear factor. Characteristically, alpha-pinene has a pine-like fragrance, contributing to the scent of evergreen trees.
In terms of health benefits, alpha-pinene can enhance concentration and focus, whereas beta-pinene is associated with mood elevation. Alpha-pinene also promotes skin absorption, making it valuable in products like cold creams and facial scrubs. Its bronchodilator properties are beneficial for respiratory issues.
There are two structural forms of pinene: alpha-pinene (more abundant) and beta-pinene, differing mainly in their solubility properties. Both forms possess unique health benefits, but alpha-pinene is especially noted for its role in cognitive function improvement, and it's abundant in substances like olives and rosemary. Furthermore, alpha-pinene can combat photoaging and improve skin condition, making it suitable for acne-prone skin due to its antibacterial properties.
Despite its advantages, alpha-pinene may cause skin allergies and potential kidney damage with excessive exposure. Overall, it serves crucial roles in the fragrance industry and has been traditionally used for respiratory tract infections.
Is Pinene Good For Sleep?
Recent Korean studies indicate that pinene, a terpene found in pine resin, may enhance sleep by reducing the time needed to fall asleep and increasing the duration of deep, non-REM sleep. Although the research does not suggest that pinene extends overall sleep duration, its relaxing effects may contribute to cancer therapies and show potential benefits for improving sleep quality and length in animal studies, particularly mice.
Pinene possesses significant sedative properties, elevates mood by boosting serotonin levels, and acts as a powerful anti-inflammatory by interacting with CB2 receptors. Additionally, it may bolster memory and offer neuroprotective benefits.
Traditional medicine has utilized essential oils rich in α-pinene and β-pinene for aiding sleep for centuries, linking sleep quality with mental health. Research shows β-pinene has antidepressant and sedative effects, making it valuable for anxiety and sleep disorders, while α-pinene also reduces anxiety but does not significantly enhance sleep quality. Terpenes like myrcene promote relaxation and drowsiness, particularly effective for those feeling stressed or needing sleep.
Recent studies suggest that phytoncides from pine, including α-pinene, act as positive modulators of GABA receptors, further supporting their sleep-enhancing effects. Inhalation of α-pinene has been shown to increase paradoxical sleep duration in rats. Overall, pinene improves sleep quality and may protect against oxidative damage to brain cells, highlighting its therapeutic potential and unique benefits among various terpenes.
📹 Terpenes in Cannabis Help Pain, Sleep and Anxiety.
Dr. Jagmeet Sethi, MD discusses how cannabis strain’s effects are determined by more than CBD and THC or Indica and Sativa.
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